An artificial vascular graft with arterial-like properties from the University of Basel in Switzerland.
At least 20% of patients undergoing cardiovascular bypass surgery lack suitable bypass material. This can be due to the patients vessel quality, previous operations or the unavailability of suitable prosthetic grafts. Currently small diameter vessels (<4.5 mm) such as the coronary artery, are not suitable for replacement by prosthetic grafts largely due to the low patency (risk of early occlusion and restenosis).
This artificial graft is a novel graft with high elasticity and a burst strength similar to a native vessel with a high patency rate. The invention at hand aims to solve the current downsides by combining a metal-alloy supporting structure with a cellulose layer that has a unique patented inner structure. The modified inner structure is key for ideal endothelization, at the same time the structure remains fully permeable for cells while being blood tight.
The graft is easy to handle (storing at room temperature) ensuring good surgical handling.