NLC seeks an entrepreneur to become CEO of a new venture solving the issue of the high number of undiagnosed people with osteoporosis. The venture will be centred around a software solution to diagnose osteoporosis, which can either complement or even replace the currently-standard DXA method as it is cheaper, more accurate, easier accessible and leads to less radiation.

The invention
Loss of bone health is a global health problem in an aging population. In 2010, 22 million women and 5.5million men were estimated to have osteoporosis in the EU; and 3.5 million new fragility fractures were sustained. The economic burden of incident and prior fragility fractures was estimated at 37 billion euros. 

Osteoporosis results from an imbalance of bone resorption and formation processes. Osteoporosis increases the risk of bone fractures, reduces mobility and quality of life quality, and increases mortality. The current standard of diagnostic, measuring bone mineral density (BMD) by dual-energy X-ray absorptiometry,  has limitations. Currently 80% of people with increased fracture risk are underdiagnosed and undertreated. 

The system executes the method for determining a pore size, a bone thickness, and speed of sound of the cortical bone. The cortical ultrasound backscatter (CortBS) analysis detects microstructural changes in cortical bone by means of a novel analysis of ultrasound backscatter spectra using conventional 3D ultrasound scanner technology. Potentially, the onset and progression of pathological changes can be detected long before the first osteoporotic fracture occurs and ideally when preventive action can still be taken. The CortBS analysis is a radiation free method that has the potential to identify patients at risk that are not recognized by dual-energy X-ray absorptiometry CortBS is adaptable to conventional 3D ultrasound systems that are widely distributed in the health sector. Data was captured using a conventional 3D ultrasound system. Validity of the data analysis has been shown on 20 human cadaver bones ex vivo. In attached the main benefits according to the inventor Prof. Raum.

The CEO position
This is a unique opportunity to build a lean startup jointly with the reputable Charite Medical University of Berlin and top advisers in the area of radiology, healthcare and software development.
As CEO you are responsible for developing and executing the overall business strategy. From defining, executing (and pivoting) the right business model to managing the process of application building,  and eventually exiting the venture.

CEO Qualifications

  • Academic qualifications
  • Experience in a healthcare startup, ideally familiar with the lean startup methodology
  • Entrepreneurial drive and a track record of developing action oriented strategy
  • Carried overall responsibility for a company, business or (development) program
  • A strong healthcare network, in Europe, North America and/or Asia. A strong understanding of the German or Austrian  ecosystem & funding landscape is a plus.
  • Interest in modern technology, ideally experienced with managing the process of app building: able to write a good specification.
  • Affinity with osteoporosis (professionally or personally) is a plus.

Practical information & Applications

The CEO we are looking for is an entrepreneur, motivated to take ownership and create impact. The remuneration is initially equity-based.
Are you ready to co-found this promising startup with us?
Please please contact Eva van Rooijen via