Osteoporosis is a very common condition. Among the population aged over 50, one in three women and one in five men will suffer a fragility fracture. At the turn of the century, 9 million fragility fractures occurred annually or one fracture every 3 seconds. The hip fracture increase is expected to grow +310% for men and +240% for woman. Early detection is vital because the highest fracture incidence is not seen in people diagnosed to have osteoporosis, but in those diagnosed to be healthy.
Current measurement methods cannot detect the onset of osteoporosis, but rather approximate the bone-loss associated relative fracture risk, typically at advanced stages of the disease progression.
The cost that osteoporosis imposes on healthcare budgets is staggering. In 2010, European Union countries spent Euro 37 billion (US$40 billion), while in 2015 the United States spent US$20 billion.
The shortcoming of ultrasound for bone imaging is the fact that it cannot give clear images when used in complex media, such as bone. That’s because the ultrasound waves bounce back in these complex environments, making it impossible to calculate how far they’ve traveled. In bone, sound waves will travel through the solid parts of the bone and then scatter whenever they hit a pore. This issue has been solved by the patented software developed by Porous GmbH. The intelligent algorithms overcome the limitations of ultrasound imaging in bone where waves are scattered making it impossible to analyze cortical bone structure. Porous GmbH solution uses quantitative ultrasound technology with patented intelligent algorithms being able to measure the cortical bone quality to a microscopic pore level without radiation hazard.
Currently finalizing product development and first first in-human validation, planned market introduction in early 2023.
Venture Partner at NLC
Christian is a life science professional, with a passion for translating science into innovations and a particular interest in digital solutions and value creation from data assets. He received his PhD in biophysical chemistry from Heidelberg University and was a postdoc at the Max Planck Society and Harvard University. With more than 16 years of cross-functional and general management experience from large global corporates (Elsevier, Merck), management consulting (BCG) and fast-growing startups (ZAGENO), Christian brings valuable expertise, including: digital product management, strategy development as well as business transformation and scaling.