Since
2021
Austria
Devices for treatment
TRL 4

Challenge

To treat patients with aortic leaking valve, cardiac surgeons perform aortic valve repair surgery, but currently, there is no possibility of verifying the success of the procedure intraoperatively. Cardiac surgeons have to re-establish the circulatory system before they can verify absence of remaining aortic insufficiency and the correct leak tightness of the sutures of the graft to the vessels. In cases where the procedure was not successful, several steps of the surgical procedure have to be redone: re-clamping the aorta, induction of cardioplegic arrest and reopening of the aortic root. This is related with increased complications and risks for the patient.

Opportunity

Currently there is no device to check the functionality of the aortic valve during cardioplegic arrest. Such a device would reduce the number of complications for patients and would decrease the duration of the procedure and its costs, by enabling to check the success of the surgery intraoperatively. 

Solution

A group of researchers and surgeons from Paracelsus Medical University have developed the Aortic Root Pressurizing Device (ARPD). The ARPD allows echocardiographic evaluation of the aortic valve by mimicking the diastolic afterload while the patient is still in cardioplegic arrest. This enables surgeons to immediately address further repair improvements if needed, without having to re-establish the patient’s circulatory system. It is a disposable and easy to use device that does not require previous training. Its installation and removal takes less than 1 minute.

Status

The AGO ARPD has been tested in 15 porcine hearts. There is an active patent and the respective PCT application has been filed.

Meet the team

Dr. Christian Dinges

Dr. Christian Dinges

Inventor

ernesto

Ernesto Urbano

Co- Inventor

johann

Johann Fierlbeck

CEO

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Alessandro Radaelli

Venture partner at NLC

Alessandro joined NLC in April 2022 and brings over 20 years of experience in the MedTech industry. His passion lies in translating clinical needs into meaningful solutions, building purpose-driven 'tribes' of early adopters and taking impactful innovations from idea to business realisation. He has lived in four European countries and has travelled to more than 20 countries with great curiosity for healthcare systems, and the local food culture.