Ventures

Kaminari Medical is innovating coronary artery disease treatment with a catheter, combining intravascular ultrasound (IVUS) and photoacoustic imaging (PA). This IVPA technology provides precise information on plaque location and structure, enabling doctors to identify and treat dangerous plaques preemptively. By enhancing the accuracy of stent placements and guiding medication therapy, IVPA is expected to prevent 50% of re-catheterizations, reducing repeated procedures and saving over €1 billion annually.

Audaxis Medical revolutionizes the treatment of stress urinary incontinence with Plielle™, a next-generation polyurethane support system. While traditional polypropylene slings often lead to chronic inflammation and tissue complications, Plielle™ offers a safer alternative by replicating the native structure and viscoelastic properties of the pelvic floor. By providing a high-performance, biocompatible solution that integrates seamlessly with human tissue, Audaxis aims to improve clinical outcomes and restore patient confidence, filling a critical gap in women’s healthcare.

Amotio addresses the challenge of revision surgeries for hip, knee, and shoulder implants with their innovative approach. Collaborating with expert revision surgeons and guided by NLC, they offer a patented solution for improved implant revision surgery. By developing unique bone cement removal devices and integrating advanced patient-specific 3D surgical planning and printing technology, Amotio aims to set a new standard for excellence in these surgeries. Their goal is to reduce complexity, trauma, and recovery time while cutting costs for healthcare providers.

Spinal cord Injury represents a large unmet medical need with approximately 1.2M new cases per year resulting mainly from motor vehicle accidents, falls and water related accidents. Currently available treatments only offer symptomatic relief but do not target the underlying pathophysiologic changes. The spinal cord injury market is predicted to reach US$3B by 2025. MLP-1236 is a First in class dual inhibitor of matrix metalloproteinases (MMP) 9 and MMP 12 and has already completed Phase 1 and Phase 2a clinical studies. In preclinical models, MLP-1236 was effective in preventing/reversing the neurodegeneration associated with spinal cord injury and ischemic stroke.

Ansana offers a smart sterilization container for surgical instruments, designed to tackle key challenges in the healthcare sector. By integrating electronic sensors, it ensures sterility in operating rooms, reducing the risk of infections by 10% and lowering the environmental impact of sterilization processes by 85%. Ansana's enhances patient safety with real-time monitoring and traceability features, with complex instruments like endoscopes, while also cutting costs for healthcare facilities in terms of labor and materials.

With over 50 million people living with Alzheimer's and numbers expected to triple by 2050, there's an urgent need for effective treatments. Alzheimer's is a leading cause of death and imposes a global economic burden of $1 trillion annually. Our novel DYRK1A inhibitor aims to slow or even reverse Alzheimer's progression by targeting key pathways with high specificity and effective blood-brain barrier penetration. This innovative small molecule offers superior disease-modifying potential, addressing current treatment limitations and providing new hope for patients and healthcare systems worldwide.

Rheumasense combines LC-MS biomarker testing with advanced machine learning to provide real-time, objective insights into rheumatoid arthritis (RA) disease activity. Our technology measures specific metabolites linked to RA progression, offering accurate, quantitative data for timely, personalized treatment adjustments. With a simple at-home blood collection kit and clinically validated testing at Mayo Clinic Laboratories, we deliver actionable results quickly and cost-effectively, improving patient outcomes and supporting proactive care.

Altach is tackling the challenge of treating damaged cartilage effectively without costly or complex procedures. Altach's solution is a simple, ready-to-use implant that makes microfracture treatment better. It's made from cartilage-like material and helps the body build new, healthy cartilage. This means fewer surgeries and better outcomes for patients.