Since
2020
Germany
Diagnostics
TRL 3

Challenge

Allergy is among the most common chronic diseases worldwide. Up to 20% of patients with allergies live with a severe debilitating form of their condition, and struggle daily with the fear of a possible asthma attack, anaphylactic shock, or even death from an allergic reaction (EAACI, 2016). Current tests to diagnose allergy such as the skin prick test and the IgE blood tests, indicate sensitisation to allergens, but not necessarily an allergic response. These tests are in the majority of cases not indicative of an actual allergy.

Opportunity

Market reports show the Allergy Diagnostics Market is anticipated to reach over $8.6 billion by 2026. In general, a molecule-based diagnostic test gives information on sensitization but not allergic reactions. There is a great need for new diagnostic solutions to replace inaccurate methods.

Solution

Researchers from the University of Bremen, supported by colleagues at the Medical University of Vienna, have developed a method and system that can directly diagnose allergies by visualising part of the allergic response (degranulation) from a blood sample. The system consists of a disposable microfluidic chip and a holography reader. With the ability to be used by more than 150 allergens this test will
enable patients to be better informed about their allergy status and enable doctors to provide the best suited treatment in a timely fashion.

Status

A third generation chip has been developed which will be tested with patients’ blood samples material.

Meet the team

Ernst (2)

Ernst Elhorst

CEO

Sander_Driesche

Dr. Sander van den Driesche

Inventor

Autorenportait_Hafner

Dr. Christine Hafner

Inventor

claas

Dr. Claas Falldorf

Inventor

BREITENEDER

Prof. Heimo Breteneder

Inventor

Vellekoop

Prof. Michael Vellekoop

Inventor

Evert

Evert Küppers

NLC Venture Partner

Pharmaceutical executive with over 18 years of successful practice in different, international work settings (large pharma, biotech start-up, pharma management consultancy) performing hands-on corporate tasks (Operations, BusDev./licensing, fundraising, org).