Since
2022
France
Devices for treatment
TRL 4

Challenge

The main treatment options for obstructive sleep apnea (OSA) are continuous positive airway pressure therapy (CPAP) and mandibular advancement devices. CPAP has a 15% initial refusal rate and long term adherence is difficult to achieve. 30% of the patients are not suitable for mandibular advancement devices. Another treatment option is surgery, which is invasive, so correlated with perioperative and postoperative complications. The most common sleep apnea surgical procedure is the uvulopalatopharyngoplasty, which has highly variable success rates

OSA affects 4% of the population. It causes severe fatigue during the day and is associated with high blood pressure, arrhythmia, stroke and heart failure. There is a medical need for more non-invasive treatment options.

Opportunity

75% of patients showed an improvement in apneas or hypopneas while using the device. Thereafter, the design and algorithm of the device is optimized to further increase the  treatment efficacy. The size of the device decreased and the algorithm automatically adapts the stimulation to the patient’s needs. The next step will be validation of this new prototype in clinical trials, obtaining CE mark/FDA approval, so it can be implemented in the clinical setting.

Solution

The solution is a non-invasive device that detects, monitors and treats obstructive sleep apnea using kinesthetic stimulation. The device consist of a cardiorespiratory recorder, a kinesthetic stimulator and a real-time processing algorithm.

Status

Meet the team

Pieter Wijffels (1)

Pieter Wijffels

Venture Partner

Pieter joined NLC in April 2020 as a Venture Partner. Before joining NLC, he spent 15 years at Philips, bringing innovation to life across the globe. He enjoys working in fast-paced environments and supporting initiatives that truly improve people’s lives.