Since
2023
Spain
Diagnostics
TRL 2

Challenge

Live-cell imaging is a research practice used in a variety of fields such as cancer research, drug discovery, fertility, and clinical diagnostics. This functional technology enables scientists to explore several aspects related to the cell such as morphology, composition and behavior. However, despite its role in advancing cellular-level research, the current cell imaging technologies are often expensive, invasive, time consuming, and require specific laboratory settings.

Opportunity

The Wavefront solution manages to fix these issues by using a computational microscope that goes way beyond being a tool for researchers. It holds transformative potential in diagnostics and disease detection. Traditional microscopy methods for imaging live-cells are expensive and time-consuming. Additionally, these traditional approaches are invasive as cells are typically stained using chemicals which impact cell integrity and reduce their usability for subsequent testing. Wavefront’s technology, on the other hand, is cell-friendly, enabling real-time images for a fraction of the current cost.

Solution

Wavefront is developing a stain-free live-cell imaging technique with a computational microscope using a quantitative-phase-imaging (QPI) patented technology. This innovative approach enables precise analysis of cellular structures with high accuracy and detail. This special type of microscope captures images, which are then reconstructed by AI software. This technique offers cost-effectiveness, operates without the need for chemicals, and preserves cell integrity. Additionally, it provides real-time imaging and offers the flexibility to be performed in any location without the necessity of a specific laboratory setting.

Status

Wavefront is in the final stages of proof of concept for its computational microscope. After testing the limits of the technology, Wavefront will build a functional prototype for both hardware and software components.

Meet the team

Wavefront2

Wilson Gomes

CEO

ManuelMartinezPhD-gomes_wilson@hotmail.com_

Manuel Martinez

Inventor Co-founder

GenaroSaavedra-gomes_wilson@hotmail.com_

Genaro Saavedra

Inventor Co-founder

Peter-Torok-gomes_wilson@hotmail.com_

Peter Torok

Inventor Co-founder

EmilioSanchez-768x768

Emilio Sanchez

Inventor Co-founder

Gina Melchner (2)

Gina Melchner

Venture Partner

Gina joined NLC in February 2020. As a Venture Partner, she works with a portfolio of Biotech and Medtech ventures. Gina also leads NLC’s Medtech Domain, ensuring we build impactful new Medtech ventures year after year. Gina holds a master’s in biotechnology from ETH Zurich and worked in management consulting as well as venture capital before joining NLC.